
Mechanical loading still reigns for muscle hypertrophy, scientists say. Hormones, ‘pump,’ not so much
Key takeaways Mechanical tension and mechanotransduction are currently the strongest evidence-based explanations for how muscles get bigger. Current evidence suggests that anabolic hormones, cell swelling (“pump”), and metabolites have little to no effect on muscle hypertrophy. A Canadian exercise scientist suggests a few ways for academics and others to disseminate


